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Anti-TIGIT Therapy: Overview of Current Clinical Evidence and Key Ongoing Trials

Listen to Dr. Jyoti D. Patel and Dr. Ani Balmanoukian as they discuss the potential role of anti-TIGIT therapies in lung cancer and other solid malignancies.
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Ani Balmanoukian, MD
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Jyoti D. Patel, MD
Released: April 15, 2022

In this episode, Jyoti D. Patel, MD, and Ani Balmanoukian, MD, discuss several studies investigating agents targeting TIGIT, an emerging immune checkpoint target with promising results in PD-L1-positive NSCLC. The episode includes a review of phase II data on the use of tiragolumab plus atezolizumab in NSCLC, the use of PD-L1 as a marker of response, the potential role of anti-TIGIT therapies in solid tumors, and ongoing trials in lung cancer including SKYSCRAPER-01, SKYSCRAPER-02, SKYSCRAPER-03, and SKYSCRAPER-05.

Information on this Educational Activity

Faculty

Ani Balmanoukian, MD

Director of Thoracic Oncology
Medical Oncology
The Angeles Clinic and Research Institute, a Cedars-Sinai Affiliate
Los Angeles, California

Ani Balmanoukian, MD, has disclosed that she has received consulting fees from AstraZeneca, Bristol-Myers Squibb, and Genentech.
Jyoti D. Patel, MD

Professor of Medicine
Division of Hematology and Oncology
Medical Director for Thoracic Oncology
Assistant Director for Clinical Research
Associate Vice Chair of Clinical Research
Department of Medicine
Robert H. Lurie Comprehensive Cancer Center
Northwestern University
Chicago, Illinois

Jyoti D. Patel, MD, has disclosed that she has received funds for research from AstraZeneca and consulting fees from AbbVie and Takeda.

Program Medium

This program has been made available online.

Acknowledgements

Provided by Clinical Care Options, LLC.

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Supported by an educational grant from
Genentech, a member of the Roche Group

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