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Targeting TIGIT: Understanding New Approaches for Inhibiting the Immune Checkpoint Pathway

Listen to Drs. Jyoti Patel and Diwakar Davar as they discuss the latest research on TIGIT, the exciting emerging target in immune checkpoint inhibitors.
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Diwakar Davar, MD
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Jyoti D. Patel, MD
Released: April 7, 2022

In this episode, Jyoti D. Patel, MD, and Diwakar Davar, MD, discuss several studies investigating agents targeting TIGIT, an emerging immune checkpoint target with promising early-phase clinical trial results. The episode includes a comprehensive explanation of TIGIT, how the TIGIT pathway functions, and the potential role of TIGIT inhibition for the treatment of cancer, including analyses from ongoing clinical trials such as CITYSCAPE, PACIFIC-8, ARC-7, and SKYSCRAPER-01.

Information on this Educational Activity

Faculty

Diwakar Davar, MD

Assistant Professor
Melanoma and Phase I Therapeutics
Division of Hematology/Oncology
Department of Medicine
University of Pittsburgh Hillman Cancer Center
Pittsburgh, Pennsylvania

Jyoti D. Patel, MD, has disclosed that she has received funds for research from AstraZeneca, and has been and advisor for Abbvie and Takeda.
Jyoti D. Patel, MD

Professor of Medicine
Division of Hematology and Oncology
Medical Director for Thoracic Oncology
Assistant Director for Clinical Research
Associate Vice Chair of Clinical Research
Department of Medicine
Robert H. Lurie Comprehensive Cancer Center
Northwestern University
Chicago, Illinois

Diwakar Davar, MD, has disclosed that he has received funds for research support from Arcus, CellSight Technologies, Checkmate Pharmaceuticals, GlaxoSmithKline/Tesaro, Immunocore, and Merck and consulting fees from Checkmate Pharmaceuticals, Finch, Shionogi, and Vedanta.

Program Medium

This program has been made available online.

Acknowledgements

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Supported by an educational grant from
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