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New Directions With PARP Inhibitors in Pancreatic Cancer

Listen to Eileen M. O’Reilly, MD, and Naureen Starling, MD, FRCP, discuss emerging therapeutic strategies involving PARP inhibitors that are being investigated for the treatment of pancreatic cancer.
Eileen M. O'Reilly, MD
person default
Naureen Starling, BSc(Hons), MBBS, MD(Res), FRCP
Released: February 21, 2022

In this episode, Eileen M. O’Reilly, MD, and Naureen Starling, MD, FRCP,  discuss emerging therapeutic strategies involving PARP inhibitor therapy in the treatment of pancreatic cancer. Topics include:

  • Current treatment landscape and testing in the United States vs the United Kingdom  
  • Testing for molecular subgroups beyond BRCAm
  • Using PARP inhibitors in earlier stages of the disease
  • Learning from other cancers, such as prostate, breast, and ovarian


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Eileen M. O'Reilly, MD

Winthrop Rockefeller Chair in Medical Oncology
Section Head, 
Hepatopancreaticobiliary/Neuroendocriine Cancers
Gastrointestinal Oncology Service
Associate Director
David M. Rubenstein Center for Pancreatic Cancer
Attending Physician, Member
Memorial Sloan Kettering Cancer Center
Professor of Medicine
Weill Medical College
New York, New York

Eileen M. O’Reilly, MD, has disclosed that she has received funds for research support from Agios, Arcus, AstraZeneca, BioNtech, BMS, Celgene, Flatiron, Genentech/Roche, Genoscience, Incyte, Polaris, Puma, QED, Silenseed, and Yiviva and consulting fees from Adicet, Alnylam, AstraZeneca, Autem, Bayer, BeiGene, Berry Genomics, Celgene, Cend, CytomX, Eisai, Exelixis, Flatiron, Genentech/Roche, Genoscience, Helio, Incyte, Ipsen, Legend Biotech, Lilly, Merck, Nerviano, QED, Rafael, Redhill, Servier, Silenseed, Sobi, Surface Oncology, Therabionics, Vector, and Yiviva.
Naureen Starling, BSc(Hons), MBBS, MD(Res), FRCP

Associate Director of Clinical Research
Department of GI Cancers
The Royal Marsden Hospital/ICR
Consultant Medical Oncologist, GI Cancers
London, United Kingdom

Naureen Starling, MD, FRCP, has disclosed that she has received consulting fees from Amgen, GSK, Lilly, MSD, Novartis, Pierre Fabre, and Servier.

Program Medium

This program has been made available online.

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