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Interim Results From the Phase III Northstar-3 (HGB-212) Study of Betibeglogene Autotemcel in Patients With Severe Transfusion-Dependent β-Thalassemia

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Interim results from the phase III Northstar-3 study showed that most patients with transfusion-dependent β-thalassemia who received betibeglogene autotemcel gene therapy produced sufficient HbAT87Q to stop RBC transfusions for ≥ 3 months.

Released: December 17, 2019

Expiration: December 15, 2020

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Jointly provided by the Annenberg Center for Health Sciences at Eisenhower and Clinical Care Options, LLC
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Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC

Karyopharm Therapeutics

Loxo Oncology subsidiary of Eli Lilly

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