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Phase I Study: Ivosidenib or Enasidenib + Standard Induction Chemotherapy in Newly Diagnosed AML With IDH1/IDH2 Mutations

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The combination of IDH inhibitors enasidenib or ivosidenib with standard 7 + 3 induction chemotherapy appears safe with response rates comparable to those expected with standard induction chemotherapy in patients with either de novo or secondary AML.

Released: December 15, 2017

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Jointly provided by the Annenberg Center for Health Sciences at Eisenhower and Clinical Care Options, LLC
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This activity is supported by educational grants from

AbbVie

AstraZeneca

Celgene

Genentech TEXT Only

Janssen Biotech Pharmacyclics Abbvie

Jazz Pharmaceuticals Inc

Novartis Pharmaceuticals Corporation

Pharmacyclics Inc

Seagen

Takeda Oncology