Welcome to the CCO Site

Thank you for your interest in CCO content. As a guest, please complete the following information fields. These data help ensure our continued delivery of impactful education. 

Become a member (or login)? Member benefits include accreditation certificates, downloadable slides, and decision support tools.


Webcast: Targeted Therapies for Migraine Prevention in the Challenging Migraineur: Focus on CGRP Blockade
  • CME

In this dynamic CME-certified video from a live symposium, expert faculty discuss the clinical application of CGRP-targeting agents in migraine prophylaxis.
Wade Cooper, DO
Merle Diamond, MD
Physicians: maximum of 1.0 AMA PRA Category 1 Credit
Released: March 10, 2020 Expiration: March 9, 2021

Learning Objectives

Upon completion of this activity, participants should be able to:
  • Identify the challenges and unmet needs for safe and effective reduction of migraine burden in patients with frequent episodic or chronic migraine who cannot tolerate or respond poorly to conventional therapies
  • Describe recent investigations into the role of CGRP in the migraine cascade and the rationale for utilizing CGRP blockade for migraine prophylaxis
  • Compare and contrast available and emerging CGRP blockers with respect to administration features, dosing intervals, and pivotal clinical trial results
  • Consider patients’ expectations, preferences, and unmet needs when selecting a CGRP blocker product for migraine prophylaxis

Information on this Educational Activity

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any relevant conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:


Wade Cooper, DO

Director, Headache and Neuropathic Pain
Clinical Associate Professor, Neurology and Anesthesiology
University of Michigan
Ann Arbor, Michigan

Wade Cooper, DO, has disclosed that he has received consulting fees from Alder, Allergan, Amgen, Lilly, and Teva and fees for non-CME/CE services from Amgen and Lilly.
Merle Diamond, MD

Clinical Assistant Professor
Department of Medicine
Rosalind Franklin University
Managing Director

Diamond Headache Clinic
AMITA Health St Joseph Hospital
Chicago, Illinois

Merle Diamond, MD, has disclosed that she has received consulting fees from Amgen, Lilly, Lundbeck, Promius, Supernus, Teva, and Upsher-Smith Laboratories and fees for non-CME/CE services from Amgen, Assertio, Lilly, Lundbeck, Supernus, and Teva.


Anne Roc, PhD
Director, Scientific Services
Anne Roc, PhD, has no relevant conflicts of interest to report.
Zachary Schwartz, MSc

Scientific Director

Zachary Schwartz, MSc, ELS, has no relevant conflicts of interest to report.
Carolyn Skowronski, PharmD

Associate Director, Scientific Services

Carolyn Skowronski, PharmD, has no relevant conflicts of interest to report.
Megan Cartwright, PhD

Senior Clinical Editor

Megan Cartwright, PhD, has no relevant conflicts of interest to report.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Target Audience

This program is intended for neurologists, headache specialists, primary care physicians, nurses, and other healthcare providers who treat migraine.


The goal of this activity is to improve participants’ knowledge of and competence in applying current and emerging CGRP-based treatment strategies in migraine prevention and treatment.


Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Credit Designation

CCO designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Program Medium

This program has been made available online.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 1.0 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from March 10, 2020, through March 09, 2021:

1. Register online at http://www.clinicaloptions.com.
2. Read the target audience, learning objectives, and faculty disclosures.
3. Study the educational activity online or printed out.
4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65% and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the posttest confirmation page. Records of all CME/CE activities completed can be found on the "CME/CE Manager" page. There are no costs/fees for this activity.

Related Content

From CCO: Companion Migraine Comorbidities slideset with highlights from Do-It-Better RealCME on Improving Migraine Treatment, and Prevention.

Jessica Ailani, MD Released: June 25, 2020

From CCO: companion migraine prophylaxis slideset with highlights from Do-It-Better RealCME on improving migraine treatment, and prevention

Wade Cooper, DO Released: June 25, 2020

Patient cases on migraine prophylaxis: beta-blockers, antiseizure medications, CGRP monoclonal antibodies (mAbs), role of shared decision-making

Wade Cooper, DO Physicians: maximum of 0.5 AMA PRA Category 1 Credits Released: May 28, 2020 Expired: May 28, 2021

Patient cases on comorbidities in migraine, including sleep disorders, depression, and more

Jessica Ailani, MD Physicians: maximum of 0.5 AMA PRA Category 1 Credits Released: May 28, 2020 Expired: May 28, 2021
Provided by Clinical Care Options, LLC

Clinical Care Options, LLC
12001 Sunrise Valley Drive
Suite 300
Reston, VA

Sophia Kelley

Supported by an educational grant from

Leaving the CCO site

You are now leaving the CCO site. The new destination site may have different terms of use and privacy policy.


Welcome to the CCO site.

You are accessing CCO's educational content today as a Guest user.

If you would like to continue with free, full access to the CCO Web sites, including free CME/CE credits, please click the button below.


More info

CCO’s educational programs are available completely free of charge on the ClinicalOptions.com, inPractice.com, and inPracticeAfrica.com Web sites. Certain features and functions are restricted for Guest users. By consenting to become a full member, you are eligible to receive CME/CE credit or participation certificates from certified activities, to register for CCO’s free live meetings and webinars, and to receive CCO’s email newsletters alerting you to new content. You can unsubscribe from our emails at any time. CCO strictly protects the privacy of our members, according to our privacy policy.

A confirmation email will be sent to . Not You?