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A Comprehensive Overview of the Bipolar Spectrum

Listen as 2 experts in psychiatry provide an overview of the bipolar spectrum, including identifying bipolar depression with mixed presentations and various treatment strategies.
Charles DeBattista, MD
Greg W. Mattingly, MD
Released: July 7, 2022

In this episode, Drs Greg W. Mattingly and Charles DeBattista have a conversation about the history and features of the bipolar spectrum. Because patients can present in mixed vignettes, diagnosis of bipolar depression can be challenging. The experts offer insight on when to hold a suspicion for bipolar depression, as well as common presentations they have seen over their years in clinical practice. The conversation then progresses to potential “triggers” of bipolar depression and culminates with a discussion of the current treatment paradigm for patients with bipolar depression: first- or second-generation antipsychotics.

Information on this Educational Activity


Greg W. Mattingly, MD

Associate Clinical Professor
Washington University School of Medicine
St Louis, Missouri
Midwest Research Group
St. Louis, Missouri

Greg W. Mattingly, MD: speaker: AbbVie, Alkermes, Corium, Eisai, Intra-Cellular, Ironshore, Janssen, Lundbeck, Neurocrine, Noven, Otsuka, Sunovion, Supernus, Takeda, Tris Pharma; consultant: AbbVie, Acadia, Alkermes, Axsome, Corium, Eisai, Intra-Cellular, Ironshore, Janssen, Lundbeck, Neos, Neurocrine, Noven, Otsuka, Redax, Rhodes, Roche, Sage, Sirona, Sunovion, Supernus, Takeda, Teva, Tris Pharma; researcher: AbbVie, Acadia, Akili, Alkermes, Axsome, Boehringer, Emalex, Idorsia, Janssen, Karuna, Lumos Labs, Medgenics, NLS-1 Pharma AG, Redax, Relmada, Roche, Sage, Sirtsei, Sunovion, Supernus, Takeda, Teva.
Charles DeBattista, MD

Chief, Depression Research Clinic
Director, Medical Student Education in Psychiatry
Professor of Psychiatry and Behavioral Sciences
Stanford University School of Medicine
Stanford, California

Charles DeBattista, DMH, MD: researcher: Biolite, Compass, Janssen, Myriad, Neurocentria, Relmada, Sage; consultant: AbbVie, Corcept.

Program Medium

This program has been made available online.


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Supported by educational grants from
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