Welcome to the CCO Site

Thank you for your interest in CCO content. As a guest, please complete the following information fields. These data help ensure our continued delivery of impactful education. 

Become a member (or login)? Member benefits include accreditation certificates, downloadable slides, and decision support tools.

Submit

eCase: Use of Valbenazine in an Older Patient With Tardive Dyskinesia

Rebecca S. Roma, MD
Released: August 31, 2021

Discussion

This case study described the successful use of a VMAT2 inhibitor in an older patient with TD who had poor insight into her TD symptoms and orofacial hyperkinesis in response to lurasidone that was worsened with pramipexole. Despite her long history of bipolar disorder, older age, and atypical antipsychotic exposure, when she developed orofacial dyskinesis after initiation of lurasidone, it was misdiagnosed as drug-induced parkinsonism and treated with discontinuation of lurasidone and initiation of pramipexole, which worsened her orofacial dyskinesis. Despite the patient’s poor insight into her TD symptoms that progressed to mouth sores and orofacial muscular stiffness and started to affect her social functioning, diagnosis, and treatment were ultimately facilitated through regular follow-ups, in-person evaluation, formal AIMS assessment, patient interviews to increase symptom awareness, and discussions about available treatments. The selective VMAT2 inhibitor valbenazine was chosen due to it once-daily dosage best suited to ensure patient adherence. Valbenazine treatment resulted in improvement of TD symptoms without noticeable adverse events.

Provided by Clinical Care Options, LLC

Contact Clinical Care Options

For customer support please email: customersupport@cealliance.com

Mailing Address
Clinical Care Options, LLC
12001 Sunrise Valley Drive
Suite 300
Reston, VA 20191

Supported by an educational grant provided by
Neurocrine Biosciences, Inc.

Leaving the CCO site

You are now leaving the CCO site. The new destination site may have different terms of use and privacy policy.

Continue

Cookie Settings