Thank you for your interest in CCO content. As a guest, please complete the following information fields. These data help ensure our continued delivery of impactful education.
Become a member (or login)? Member benefits include accreditation certificates, downloadable slides, and decision support tools.
In the landmark real-world REVEAL study of 3653 untreated hepatitis B surface antigen (HBsAg)–positive adults in Taiwan, 2 key risk factors for HCC were cirrhosis and a high HBV DNA level. The threshold for significant increase in HCC risk occurs at an HBV DNA of 10,000 copies/mL, or approximately 2000 IU/mL. Above that threshold, we can see that HCC risk increases dramatically.6