Clinical Impact of New Rheumatoid Arthritis Findings From EULAR 2020*

June 3-6, 2020; Virtual Meeting
Review the latest RA management data with Capsule Summaries and expert-authored commentaries covering key studies from EULAR 2020.

Rheumatoid Arthritis Highlights From EULAR 2020

Capsule Summary Slidesets

In this descriptive analysis, upadacitinib 30 mg was associated with a higher rate of serious and opportunistic infections, including herpes zoster, compared with the 15 mg dose.

Released: July 7, 2020

In RA patients with high disease activity by DAS28, observed absolute risk of developing a VTE event within 1 year of rheumatologist visit was 1 in 100.

Released: August 13, 2020

Overall, 7% of adults self-reported biologic-associated fatigue. Compared with patients not reporting fatigue, they were younger and more frequently smoked, were more likely to have Crohn disease, and used infliximab, rituximab, or vedolizumab.

Released: August 13, 2020

Numerically lower probability of discontinuation with JAK inhibitors vs TNF inhibitors in adjusted analysis of 25,521 patients with rheumatoid arthritis.

Released: July 1, 2020

Analysis of individual case safety reports in worldwide pharmacovigilance database examines thromboembolic events with tofacitinib and baricitinib.

Released: July 1, 2020

Among patients receiving DMARDs for RA, risk of herpes zoster was significantly higher with JAK inhibitors, monoclonal TNF inhibitor antibodies, B-cell­–targeted therapy, T-cell costimulation modulation, or IL-6 inhibition.

Released: July 1, 2020

At 12 weeks, change in DAS28-CRP with upadacitinib was noninferior to (primary endpoint) and also superior to (secondary endpoint) abatacept. Upadacitinib was also associated with superior rate of clinical remission (DAS28-CRP < 2.6).

Released: August 17, 2020

Efficacy of add-on therapy with JAK1 inhibitor filgotinib sustained through Week 52 with no new safety signals in patients with rheumatoid arthritis and inadequate response to methotrexate.

Released: July 13, 2020
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Sophia Kelley
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skelley@clinicaloptions.com
www.clinicaloptions.com

Supported by an educational grant from
AbbVie Inc.
Gilead Sciences, Inc.

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