Clinical Impact of New Rheumatoid Arthritis Data from APLAR 2019, JCR 2019, and EULAR 2019*

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APLAR 2019: Brisbane, Australia; April 8-11, 2019; JCR: Kyoto, Japan; April 15-17, 2019
EULAR: Madrid, Spain; June 12-15, 2019
Review the latest RA management data with Capsule Summaries, downloadable slides, and expert analysis covering key studies from APLAR 2019, JCR 2019, and EULAR 2019.

Rheumatoid Arthritis

Capsule Summary Slidesets

Withdrawal of csDMARDs had no significant effect on ongoing clinical response compared with continuation of csDMARDs or use of sarilumab monotherapy.

Released: June 27, 2019

IV formulation of prednisolone was more effective than standard IM methylprednisolone for treating RA flares.

Released: July 1, 2019

Add-on therapy with JAK1 inhibitor filgotinib demonstrated improved responses compared with placebo in patients with RA who had inadequate response to methotrexate.

Released: June 18, 2019

Addition of JAK1 inhibitor to methotrexate improved ACR20 responses compared with methotrexate alone in methotrexate-naive patients with RA.

Released: June 27, 2019

Tofacitinib monotherapy after methotrexate withdrawal does not worsen disease activity in RA patients who previously achieved low disease activity with tofacitinib plus methotrexate.

Released: June 18, 2019

Prednisone tapering may be feasible in some RA patients with low disease activity or remission on tocilizumab, although continuous treatment provided superior disease control.

Released: June 19, 2019

SC formulation of CT-P13 demonstrated noninferior efficacy compared to IV formulation for change in DAS28-CRP from baseline to Week 22 in patients with rheumatoid arthritis.

Released: June 21, 2019

Baricitinib demonstrates acceptable safety in RA patients exposed for up to 7 yrs

Released: June 28, 2019

Analysis of pooled data from 5 phase III RCTs in RA patients suggests similarities and differences in safety profile of upadacitinib vs methotrexate or adalimumab.

Released: July 1, 2019

Monotherapy with the investigational JAK1 inhibitor upadacitinib showed sustained clinical improvements and safety outcomes through 48 weeks in patients with RA with inadequate response to methotrexate.

Released: June 24, 2019
Provided by the Annenberg Center for Health Sciences at Eisenhower

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