Emerging Insights on Adverse Events During ART and Implications for Treatment

Recent data presented at CROI 2021 provide insights on the clinical significance of INSTIs and weight gain. Here are my takeaways regarding cardiovascular and metabolic implications of INSTI-associated weight gain.

Darcy Wooten, MD Released: May 5, 2021

Healthcare professionals need better understanding of the processes involved with weight gain in patients taking antiretroviral therapy. New and upcoming data are providing valuable insights.

Gregory Huhn, MD, MPHTM Released: June 17, 2021

Recent trials of switch strategies involving 2-drug regimens aim to maintain strong virologic suppression while minimizing adverse events and maximizing tolerability. Here’s my take.

Pedro Cahn, MD, PhD Released: September 28, 2021

As our patients with HIV achieve longer life expectancies, the potential for drug–drug interactions increases as non-HIV–associated comorbid conditions arise.

Fidelia Bernice, PharmD Released: January 6, 2022

Watch this dynamic faculty discussion on the impact of emerging ART safety and tolerability data on ART initiation and switch strategies.

Joseph J. Eron, Jr., MD Darcy Wooten, MD Physicians: maximum of 1.0 AMA PRA Category 1 Credit™ Registered Nurses: 1.0 Nursing contact hour Pharmacists: 1.0 contact hour (0.1 CEUs) Released: May 11, 2021 Expired: May 10, 2022

Introduction

INSTIs and Metabolic Toxicity

NRTIs and Metabolic Toxicity

Switching ART for Tolerability

Switching ART for Comorbidities

Gain expert insight on the impact of emerging ART safety and tolerability data on ART initiation and switch strategies.

Joseph J. Eron, Jr., MD Darcy Wooten, MD Released: May 11, 2021

Review expert discussion on how new data from IAS 2021 expand our understanding of the adverse event profiles of specific ART regimens, with particular focus on weight, BMI, insulin resistance, and other metabolic parameters.

Eric S. Daar, MD Physicians: maximum of 0.75 AMA PRA Category 1 Credits™ Registered Nurses: 0.75 Nursing contact hours Pharmacists: 0.75 contact hours (0.075 CEUs) Released: September 22, 2021 Expired: September 21, 2022

Review downloadable slides on adverse events associated with current and emerging ART regimens.

Eric S. Daar, MD Released: September 22, 2021

Gain expert insight on new data from fall 2021 HIV conferences that expand our understanding of adverse events associated with ART, with particular emphasis on weight gain, metabolic complications, and pregnancy.

Gregory Huhn, MD, MPHTM Physicians: maximum of 0.75 AMA PRA Category 1 Credits™ Registered Nurses: 0.75 Nursing contact hours Pharmacists: 0.75 contact hours (0.075 CEUs) Released: December 22, 2021 Expired: December 21, 2022

Review downloadable slides on safety of ART regimens, including recent data on weight gain, metabolic complications, and pregnancy.

Hear insights and answers to audience questions from Joseph J. Eron, Jr., MD, and Darcy Wooten, MD, on HIV ART safety and tolerability including recent data on weight gain and metabolic implications with INSTIs and NRTIs.

Joseph J. Eron, Jr., MD Darcy Wooten, MD Released: July 6, 2021

Hear insights and answers to audience questions from Fidelia Bernice, PharmD, and Aadia I. Rana, MD, on HIV ART safety and tolerability including recent data on nephrotoxicity and safety with long-acting injectables.

Fidelia Bernice, PharmD Aadia I. Rana, MD Released: November 16, 2021