ICAAC, IDWeek, and the European AIDS Conference 2015*

September 17-October 24, 2015; San Diego, California; Barcelona, Spain
Review the clinical impact of new HIV-related data presented at 3 scientific meetings in the fall of 2015: ICAAC, IDWeek, and the European AIDS Conference. This program includes Capsule Summaries, downloadable slidesets, and an expert analysis text module.

Fall 2015 HIV Update

Capsules

In this pilot study, all 20 patients experienced virologic suppression (HIV-1 RNA < 50 copies/mL) by Week 8 of initial dolutegravir plus lamivudine therapy and maintained virologic suppression through Week 24 of treatment; there were no serious adverse effects.

Released: October 23, 2015

High baseline HIV-1 RNA (≥ 100,000 copies/mL) or low CD4+ cell count (< 200 cells/mm3) were associated with a lower proportion of BMS-663068-treated patients with HIV-1 RNA < 50 copies/mL at Week 48

Released: October 23, 2015

Although rare, virologic failure was associated with emergence of integrase gene mutations.

Released: October 27, 2015

Secondary measures of cognitive function and patient-reported cognitive outcomes also did not differ according to treatment allocation.

Released: October 26, 2015

In this randomized phase III trial, the switch to dolutegravir/abacavir/lamivudine was associated with a higher frequency of treatment discontinuation due to adverse events but higher treatment satisfaction score.

Released: October 22, 2015

Rates of osteoporosis in the BMD substudy population and fracture in the overall START population did not differ statistically between groups.

Released: October 27, 2015

Switching to the TAF-containing regimen improved renal and bone markers, but increased lipids.

Released: October 21, 2015

Switch associated with reduced pill burden, greater treatment satisfaction, improvement in urinary markers of renal function, but more frequent AEs.

Released: October 26, 2015
Jointly provided by the Annenberg Center for Health Sciences at Eisenhower and Clinical Care Options, LLC
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Annenberg Center for Health Sciences at Eisenhower
39000 Bob Hope Dr
Dinah Shore Bldg.
Rancho Mirage, CA 92270

Alma Perez, Accreditation Specialist
(760) 773-4506
(760) 773-4550 (Fax)
ce@annenberg.net
http://www.annenberg.net/

Educational grant provided by:
Bristol-Myers Squibb
ViiV Healthcare

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