23rd International AIDS Conference: Virtual

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July 6-10, 2020; Virtual
Including Capsule Summaries, on-demand audio, a comprehensive downloadable slideset, and ClinicalThought commentaries, this program provides expert insight on the most clinically important topics from AIDS 2020: Virtual.
Daniel R. Kuritzkes, MD
Babafemi Taiwo, MBBS
David A. Wohl, MD

Highlights

Slidesets Phase IIb Protocol 011: Islatravir Plus Doravirine Following Islatravir, Doravirine, Lamivudine Induction in Treatment-Naive Patients Demonstrates Very Low HIV-1 RNA Levels in Patients With Wk 48 Protocol-Defined Virologic Failure
Slidesets AIR: No Impact of Switching From 3-Drug to 2-Drug ART on Adverse Disease Outcomes in Virologically-Suppressed Persons With HIV
Slidesets Pooled Wk 48 Analysis of Switch to BIC/FTC/TAF in Virologically Suppressed Patients Aged 65 Yrs or Older
Slidesets OPERA: Excess Weight Gain Observed Immediately After Switch From TDF to TAF in Virologically Suppressed Adults Regardless of INSTI Use
Slidesets DRIVE-SHIFT: Modest Weight Gain Observed Through Wk 144 After Switch to DOR/3TC/TDF in Virologically Suppressed Adults
Slidesets TANGO: Metabolic Parameters Improve at Wk 48 Following Switch to DTG/3TC, Especially From Boosted Baseline ART
Slidesets Phase III ADVANCE: 96-Wk Primary Efficacy Analysis of DTG + FTC/(TAF or TDF) vs EFV/FTC/TDF in ART-Naive PWH in South Africa
Slidesets HPTN 083: Long-Acting Injectable CAB Superior to Daily Oral TDF/FTC as PrEP in MSM and TGW at High Risk of HIV Infection
Slidesets Tsepamo: DTG Exposure at Conception Associated With Small but Stabilizing Elevation in Neural Tube Defect Prevalence in Analysis Through April 2020
Slidesets Phase I Pharmacokinetic Study of Novel HIV-1 Capsid Inhibitor Lenacapavir Supports Potential for Every-6-Month SC Dosing

Patients switching from TDF to TAF in the OPERA cohort experienced an increase in weight of about 2 kg over 9 months, but then the rate of weight gain stabilized to be similar to the rate observed before the switch. How should these data inform ART decisions in clinical practice?

Daniel R. Kuritzkes, MD Released: August 11, 2020

In this downloadable slideset, CCO’s expert faculty members summarize key studies from this important conference, including new data on the following hot topics: current ART in principal populations, including older patients and women who become pregnant; metabolic outcomes during ART; HIV and COVID-19; investigational ART strategies; and HIV prevention.

Babafemi Taiwo, MBBS David A. Wohl, MD Released: July 24, 2020
Provided by Clinical Care Options, LLC
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Clinical Care Options, LLC
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Sophia Kelley
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skelley@clinicaloptions.com
www.clinicaloptions.com

Produced in collaboration with
Educational grant provided by:
Gilead Sciences
ViiV Healthcare
Merck Sharp & Dohme Corp

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