20th International AIDS Conference (AIDS 2014)

July 20-25, 2014; Melbourne, Australia
CCO is the official provider of online scientific analysis of AIDS 2014, through Capsule Summaries, downloadable slides, and expert faculty analysis of key studies on HIV treatment and prevention.

Highlights of AIDS 2014

Capsules

Virologic failure was infrequent with both treatment strategies.

Released: July 29, 2014

Efficacy and tolerability appear comparable to that seen in HCV-monoinfected populations with no significant impact on control of HIV disease.

Released: July 22, 2014

Sofosbuvir plus ribavirin administered for 12 or 24 weeks depending on HCV genotype and treatment experience was associated with SVR12 rates of 84% to 89% in this coinfected population.

Released: July 23, 2014

This negative study of an NRTI-sparing strategy in patients with CCR5-tropic virus was closed early by the independent data and safety monitoring committee.

Released: July 24, 2014

Patients who maintained HIV-1 RNA < 50="" copies/ml="" experienced="" no="" increase="" in="" virologic="" failure,="" whereas="" even="" transient="" increases=""> 200 copies/mL did increase risk.

Released: July 25, 2014

The findings were limited by the unknown contribution of adherence, unknown causes for antiretroviral switching, and unknown role of drug resistance in switching and/or subsequent virologic failure.

Released: July 24, 2014

No cases of virologic failure with dolutegravir in patients receiving NRTI-only background regimens, including among patients receiving NRTIs with reduced susceptibility.

Released: July 24, 2014

Race, high baseline HIV-1 RNA level, incomplete self-reported adherence, and low levels of genotypic resistance to NRTIs at baseline significantly predicted failure of NRTI-based second-line therapy by 96 weeks

Released: July 25, 2014

Persons at higher sexual risk were more likely to elect to take and adhere to PrEP

Released: July 25, 2014

In patients with normal BMI before starting ART, weight gain in the first year of ART was significantly associated with increased risk of cardiovascular disease.

Released: July 25, 2014
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Produced in collaboration with
Educational grant provided by:
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