2017 Annual Meeting of the American Association for the Study of Liver Diseases*

October 20-24, 2017; Washington, DC
Review Capsule Summaries, download slides, and read ClinicalThought commentaries on key studies from Washington, DC 2017.

Hepatitis C

Capsules

SVR on DAA-only regimens provided a 71% reduction in de novo HCC risk.

Released: October 27, 2017

At 3 years of follow-up, 37% of participants self-reported injection drug use, with an overall reinfection rate of 2.3 per 100 person-years.

Released: October 27, 2017

Treatment generally well tolerated with no loss of HIV-1 RNA suppression.

Released: October 25, 2017

HCC incidence similar with DAAs vs IFN in cirrhotic patients and regardless of whether patients achieved SVR.

Released: October 27, 2017

No benefit noted with extension of treatment from 8 weeks to 12 weeks among noncirrhotic patients.

Released: October 27, 2017

Clinical cohort study observed no additional benefit with use of ribavirin in cirrhotic patients, nor any negative impact of baseline RASs.

Released: October 26, 2017

In this single-center study from Johns Hopkins, one third of HCV/HIV-coinfected patients did not start HCV treatment despite adherence, nursing and pharmacy support models.

Released: October 26, 2017

Large observational cohort provides clear evidence of clinical benefits of curative DAA therapy.

Released: October 27, 2017

1-year mortality risk in patients with decompensated cirrhosis 61% lower with DAA therapy vs pre-DAA era treatment.

Released: October 27, 2017

Reduction in mortality appeared greater for liver-related vs nonliver-related events.

Released: October 27, 2017

SVR12 rate of 98% with no grade 3/4 adverse events at interim analysis.

Released: October 27, 2017
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