Learning Objectives
Upon completion of this activity, participants should be able to:
- Discuss the current limitations of treatment for advanced or metastatic sarcomas and the need for additional therapies
- Apply clinical trials data evaluating the role of adjuvant chemotherapy according to histological subtype when treating patients with sarcoma
- Describe the clinical evidence for using molecularly targeted therapies in sarcomas
- Interpret the latest data on the safety and efficacy of novel targeted therapies for the treatment of sarcomas
Topics covered include:
- Sarcoma Introduction and Background
- Conventional Treatment Approaches in Soft Tissue Sarcomas
- New Chemotherapeutic Agents in Advanced Soft Tissue Sarcoma
- Emerging Targeted Therapy for Sarcoma
- Tyrosine Kinase Inhibitors
- Role of TKIs in the Treatment of GISTs
- Role of TKIs in the Treatment of Soft Tissue Sarcomas
- Inhibitors of Heat Shock Protein
- Inhibition of the mTOR Pathway
- Antibody Therapies
- Conclusions
Abstract