Learning Objectives
Upon completion of this activity, participants should be able to:
- Explain the significance of HER2 in breast cancer
- Recall current recommendations for establishing HER2 status
- Discuss results of adjuvant studies in HER2-positive breast cancer
- Describe the safety profile of HER2-targeting agents
Topics covered include:
- Introduction
- Biology of HER2 Receptor Tyrosine Kinase
- Testing for HER2
- Clinical Studies of Trastuzumab in Metastatic Breast Cancer
- Adjuvant Trastuzumab Clinical Studies
- Trastuzumab Cardiotoxicity
- Strategies for Individual Patient Management
- Future Directions
- Treatment Options After Progression on Trastuzumab
- Conclusion