Learning Objectives
Upon completion of this activity, participants should be able to:
- Review the implications of new data suggesting prognostic significance of selected genetic alterations in malignancies such as pediatric acute lymphoblastic leukemia
- Describe biological markers with the potential to predict response to treatment with targeted therapeutic agents in various tumor types
- Recognize the utility of magnetic resonance imaging in predicting response to therapy in patients with glioblastoma
- Discuss the feasibility of applying molecular profiling of refractory tumors to identify targets for therapy
Topics covered include:
- Identification of JAK Mutations in Relapsed Pediatric ALL
- Genetic Markers Associated With an Impaired Response to EGFR Inhibitors in mCRC
- Validation of Ovarian Cancer Biomarkers for Early Screening
- Molecular Profiling of Refractory Tumors to Identify Targets for Therapy
- Inherited DICER1 Mutations in Familial Pleuropulmonary Blastoma
- Use of Imaging Analysis in Glioblastoma to Predict Treatment Response
- Conclusion