Advances in the Management of Bone Health and Skeletal Complications in Cancer

CME-Certified Interactive Virtual Presentations:

Advances in the Management of Bone Health in Multiple Myeloma

James Berenson, MD, presents cases to illustrate key concepts of bone health in cancer patients, particularly those with multiple myeloma. Click here to begin.

	Downloadable CCO Slideset:
		Advances in the Management of Bone Health in Multiple Myeloma Review the incidence, pathophysiology, and current management of bone complications in multiple myeloma patients. In addition emerging targeted therapies and their modes of action are discussed. Click here to download slides.

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Management of Bone Health in Prostate Cancer Matthew R. Smith, MD, PhD

Management of Bone Health in Breast Cancer Robert E. Coleman, MD, FRCP

Spanning the Spectrum of Care: Clinical Advances and Practical Applications in Lymphoma 

CME-Certified Modules:

Mechanisms of Action and Clinical Advances in the Treatment of Non-Hodgkin’s Lymphomas Deborah A. Frieze, PharmD, BCOP, and Alice Mohr, RN, MSN, FNP-BC, provide a broad overview of standard and emerging agents and approaches for the treatment of non-Hodgkin’s lymphomas.

Clinical Considerations and Implications for Optimizing Outcomes in Patients With NHL Alice Mohr, RN, MSN, FNP-BC, and Deborah A. Frieze, PharmD, BCOP, review dosing regimens, critical safety issues, appropriate preventive care, and supportive care measures associated with the use of various therapeutic modalities for the treatment of non-Hodgkin’s lymphoma.

CME-Certified Interactive Virtual Presentations:

Evolving Options and Challenges in Mantle Cell Lymphoma Listen to a virtual presentation by Andre Goy, MD, as he provides a comprehensive overview of evolving treatment options for patients with mantle cell lymphoma, and test your knowledge of treatment options in the cases he presents.

Evolving Options and Challenges in Mantle Cell Lymphoma Downloadable slideset on the standards of care and emerging novel therapies for the treatment of mantle cell lymphoma

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CCO Downloadable Slideset:

Overview of Treatment Options and Clinical Considerations for Managing NHL Patients Review a comprehensive overview of current standards of care for lymphoma, including nursing considerations, such as dosing schedules, adverse effects, and improving patient quality of life.

Evolving Treatment Options and Future Directions in Mantle Cell Lymphoma

CME-Certified Modules:

State-of-the-Art First-line Treatment of MCL: Current and Novel Approaches  

Andrew D. Zelenetz, MD, PhD, reviews the latest data on current and novel therapeutic approaches for frontline treatment of mantle cell lymphoma.

Steven H. Bernstein, MD, explores current recommendations and options for the treatment of advanced mantle cell lymphoma and discusses what recent clinical trial results may signify for patients.

The Role of Maintenance Therapy and Individualization of Therapy in Mantle Cell Lymphoma

Sven de Vos, MD, PhD, reviews the current status of maintenance therapy for mantle cell lymphoma and explores new developments in prognostic measures and markers that may lead to the individualization of therapy.

Practical Nursing Management Considerations in Mantle Cell Lymphoma

CCO Downloadable Slideset:

Practical Nursing Management Considerations in Mantle Cell Lymphoma

Download slides on important nursing considerations for patients who are receiving medical therapy for mantle cell lymphoma.

A Call to Action: Preventing Bone Loss and Skeletal-Related Events in Patients With Prostate Cancer: Highlights From the Symposium 

CME-Certified Slideset Module:

A Call to Action: Preventing Bone Loss and Skeletal-Related Events in Patients With Prostate Cancer: Highlights From the Symposium
Expert faculty provide an overview of the bone microenvironment, treatment-related bone loss, prevention of metastatic disease, and evolving treatment options for managing bone health in prostate cancer patients.

A Call to Action: Preventing Bone Loss and Skeletal-Related Events in Patients With Prostate Cancer: Highlights From the Symposium Download slides focused on the mechanisms underlying the bone microenvironment and how to best manage bone health and skeletal-related events in prostate cancer patients.

Current Treatment Options in Acute Lymphoblastic Leukemia

Expert review and Interactive Virtual Presentations on treatment options in acute lymphoblastic leukemia.

CME-Certified Module:

Current Treatment Options in Acute Lymphoblastic Leukemia

Dan Douer, MD, reviews current standards of care for adults and children with ALL and explores changes in the treatment landscape with the potential to improve outcomes.

CME-Certified Interactive Virtual Presentations:

Allogeneic Transplantation for Ph+ Acute Lymphoblastic Leukemia

Jacob M. Rowe, MD, FACP, explores current thinking regarding treatment strategies for adults with acute lymphoblastic leukemia.

ALL in Special Populations: Adolescents/Young Adults and Older Adults

Adele K. Fielding, MB BS, PhD, FRCP, FRCPath, reviews strategies to improve treatment outcomes in 2 special patient populations affected by ALL: young adults and the elderly.

Downloadable PowerPoint Slidesets:

Allogeneic Transplantation for Ph+ Acute Lymphoblastic Leukemia Download a slide presentation by Jacob M. Rowe, MD, FACP, focusing on allogeneic transplantation in patients with Philadelphia chromosome–positive ALL.

ALL in Special Populations: Adolescents/Young Adults and Older Adults Download a presentation by Adele K. Fielding, MB BS, PhD, FRCP, FRCPath, in which she reviews treatment strategies in 2 special patient populations affected by ALL: young adults and the elderly.

2009 American Society of Clinical Oncology Annual Meeting

CCO's independent coverage of the 2009 Clinical Oncology meeting includes Capsule Summaries of key presentations, as well as Expert Analyses, Slides, Expert Recaps, and audio Expert Highlights that focus on key issues highlighted at the conference.

• Breast Cancer
  Robert S. Mocharnuk, MD, William J. Gradishar, MD, FACP, Kathy D. Miller, MD, Mark D. Pegram, MD 
• Colorectal Cancer
  Anthony El-Khoueiry, MD, Edward Chu, MD, Richard M. Goldberg, MD, Alan P. Venook, MD, Anthony El-Khoueiry, MD
• Hematologic Malignancies
  Edward A. Stadtmauer, MD, Kenneth Anderson, MD, Andre Goy, MD, Susan M. O’Brien, MD
• Lung Cancer
  Barbara J. Gitlitz, MD, David R. Gandara, MD, Ramaswamy Govindan, MD, Corey J. Langer, MD, FACP

Integrating Novel Approaches to Therapy Into the Multidisciplinary Treatment of Sarcomas

Suzanne George, MD, reviews current and evolving treatment of sarcoma.

Multidisciplinary Strategies in the Management of Patients With Hepatocellular Carcinoma: A Video Roundtable

Expert faculty members review and explore regional and systemic treatment strategies for the clinical management of patients with hepatocellular carcinoma.

Now Available!

Video Panels:

Expert Guidance in Defining and Treating Castrate-Resistant Prostate Cancer

CME-Certified Module:

Understanding Key Issues in the Treatment of Castrate-Resistant Prostate Cancer David I. Quinn, MD, PhD, explores current approaches for managing patients with castrate-resistant prostate cancer.

CME-Certified Virtual Presentation:

Expert Guidance in Defining and Treating Castrate-Resistant Prostate Cancer Nicholas J. Vogelzang, MD, reviews the standards of care and emerging novel therapies for the treatment of castrate-resistant prostate cancer.

Expert Guidance in Defining and Treating Castrate-Resistant Prostate Cancer Downloadable slideset on the standards of care and emerging novel therapies for the treatment of castrate-resistant prostate cancer.

Coming Soon!

Interactive Decision Making Tool

Treatment Paradigms in Recurrent GBM: Today’s Options and Tomorrow’s Promising Directions

Through 3 Virtual Presentations and associated downloadable slidesets and an audio archive, CCO’s expert faculty members explore current thinking regarding the treatment of glioblastoma.

CME-Certified Virtual Presentations:
Glioblastoma: Understanding the Challenge

David Schiff, MD, provides a clinical overview of glioblastoma and reviews the genetic pathways involved in its pathogenesis, along with a discussion of MGMT methylation as a prognostic biomarker and tools for predicting survival in patients with glioblastoma.

Current Treatment Options and Recommendations for Patients With GBM

Tracy Batchelor, MD, MPH, reviews current treatment options and evidence-based recommendations for recurrent GBM.

Clinical Explorations With Targeted Agents in Recurrent GBM

Timothy Cloughesy, MD, reviews targeted agents under investigation for the treatment of glioblastoma and discusses the issue of resistance when using these drugs in this setting.

Downloadable Powerpoint Slidesets:

David Schiff, MD, reviews the epidemiology, genetic factors, and prognostic biomarkers of glioblastoma.

Tracy Batchelor, MD, MPH, discusses current treatment standards for patients with glioblastoma.

Timothy Cloughesy, MD, discusses investigational targeted agents for recurrent glioblastoma.

Downloadable Audio Archive:

Expert Insights: Issues in the Management of Glioblastoma
Patrick Y. Wen, MD discusses important issues in the management of patients with glioblastoma, including current treatment options, the role of biomarkers in selecting optimal treatment, and the future of targeted therapies.

2008 Chicago Multidisciplinary Symposium in Thoracic Oncology

CCO’s expert faculty members explore results presented at the 2008 Thoracic Oncology meeting through 3 Conference Reports and a downloadable slideset.

CME-Certified Conference Reports:

• Multimodality Therapy in Non-Small-Cell Lung Cancer
  Jeffrey D. Bradley, MD. and Benjamin Movsas, MD, review and discuss recent data on combined therapeutic approaches for non-small-cell lung cancer.
  
  
• Integration of Targeted Therapy and Traditional Chemotherapy in Advanced Non-Small-Cell Lung Cancer 
  Join Ramaswamy Govindan, MD, and Giorgio V. Scagliotti, MD, PhD, as they review the most relevant new data on the use of targeted therapies for the treatment of non-small-cell lung cancer.
  
  
• Advances in Small-Cell Lung Cancer and the Role of Marker Analysis in Advanced Non-Small-Cell Lung Cancer
  Expert faculty members respond to frequently asked questions about HIV tropism, tropism testing, and the implications for clinical management of patients.
  
  

Downloadable PowerPoint Slideset:
CCO Independent Conference Coverage of the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology

Downloadable slideset highlighting some of the most significant data presented on multimodality therapy, targeted therapy, and the utility of molecular markers in lung cancer.

Beyond Chemotherapy: Current and Future Molecular-Targeted Therapy in Ovarian Cancer

Through 4 downloadable slidesets, CCO’s expert faculty members focus on the role of molecular therapies in the treatment of ovarian cancer.

• The Need for Molecular-Targeted Therapy
  Michael V. Seiden, MD, PhD, reviews the role of molecular-targeted therapy in ovarian cancer.
  
  
• VEGF Targeted Therapy in Ovarian Cancer: Basis & Directions
  Robert A. Burger, MD, discusses the rationale for using VEGF inhibitors in ovarian cancer and reviews current phase II and III trials evaluating these agents in the frontline and recurrent setting.
  
  
• Targeting EGF and Other Signal Transduction Pathway
  Thomas J. Herzog, MD, discusses targeting EGF and other approaches such as Src inhibition, c-Met inhibition, PARP inhibition, and mTOR inhibition as therapy for ovarian cancer.
  
  
• Immunologic-Targeted Therapy in Ovarian Cancer
  George Coukos, MD, PhD, discusses immunologic-targeted therapy as a therapeutic strategy for ovarian cancer.

Bone Health and Skeletal Complications in Cancer: Insights Into Pathogenesis, Advances in Management

This Treatment Update helps clinicians apply current thinking regarding maintaining and optimizing bone health in cancer patients through 4 CME-certified educational modules.

• Breast Cancer and Bone Health: New and Emerging Treatment Options
  
• Optimizing Bone Health in Patients With Prostate Cancer
  
• Bone Complications in Multiple Myeloma
  
• Beyond Breast and Prostate Cancer: Bone Health in Other Solid Tumors
  

Hematology

• Advances in Lymphoproliferative Disease: From Molecular Pathogenesis to Multitargeted Treatment
  Through 5 text-based modules, 5 downloadable slidesets, and a debate discussion, CCO's expert faculty members explore current and novel agents used to treat leukemias, lymphomas, and other lymphoproliferative diseases.
  
  
• Clinical Controversies in the Treatment of Anemia: Appropriate Use of ESAs in a Time of Change
  Expert faculty discuss an overview of the etiology and epidemiology of anemia, the role of iron therapy in treating cancer-related anemia, and future directions for ESA therapy in these patients as determined by guidelines recommending their use and recent data from clinical trials and meta-analyses. A case-based presentation also is included to explore the appropriate use of ESAs in oncology patients. 
  
  
• Novel Approaches in Frontline Multiple Myeloma Therapy: Understanding the Options and Implications for Transplantation
  Through a CME-certified educational module and 3 Interactive Case Challenges, CCO's expert faculty members explore recent thinking regarding frontline therapy of multiple myeloma.
  
  
  

Oncology
 

• Current Research Directions in Glioblastoma Multiforme: Evolutions in Targeted Therapy
  Review expert discussions and a downloadable slideset on GBM.
  
  
• Translating Science Into Clinical Practice: Recent Lessons in EGFR Inhibition, Multitargeted TKIs, and the Tumor Microenvironment
  Through 4 CME-certified educational modules and accompanying downloadable slidesets, CCO's expert faculty members explore the use of targeted approaches in the treatment of cancer.
  
  
• Improving Survival in Colorectal Cancer Through Optimal Management of Liver Metastases
  These Interactive Case Challenges allow you to consider the appropriate treatment decisions for colorectal cancer patients with liver metastases. Compare your answers with those of other participants and receive expert feedback from the faculty members.
  
  
• Cases in Point: Risk Factors, Surveillance Strategies, and Treatment Options for Hepatocellular Carcinoma
  Review monitoring and surveillance recommendations for HCC and emerging strategies for treatment and management, then download slides for use in your own self-study or presentations.
  
  
• Managing Ovarian Cancer Recurrence: Coupling Novel Therapeutics With Optimal Treatment Decisions
  This new Treatment Update delivers an overview of current thinking regarding management of recurrent ovarian cancer through 3 CME-certified educational modules and a downloadable slideset. 
  
  

• 2009 American Society of Clinical Oncology Annual Meeting*
   
  
• 2009 Gastrointestinal Cancers Symposium*
  
  
• 2008 Annual Meeting of the European Society for Medical Oncology* 
  
  
• 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology*
   
  
• 2008 San Antonio Breast Cancer Symposium*
  
  
• 2008 American Society of Hematology Annual Meeting*
  
  
• 2008 International Symposium on Supportive Care in Cancer*
  
  
  
  

*CCO is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.

Liver Metastases in CRC

• Management of Initially Unresectable Liver Metastases in a 65-Year-Old Woman With Colorectal Cancer
• A 63-Year-Old Woman With Colorectal Cancer and Metachronous Liver and Lung Metastasis
  
  

Multiple Myeloma

• Clinical Management of a 59-Year-Old Male Patient With Multiple Myeloma and Renal Dysfunction
• Treatment of Newly Diagnosed Multiple Myeloma in a 78-Year-Old Female
  

Topics

• Breast Cancer
• Colorectal Cancer
• Gastrointestinal Cancer
• Genitourinary Cancer
• Glioblastoma
• Gynecologic Cancer
• Head and Neck Cancer
• Hematologic Malignancies
• Heptocellular Cancer
• Leukemias 
• Lung Cancer
• Lymphomas
• Melanoma and Other Skin Cancers
• Multiple Myeloma
• Oncology Nursing
• Other Oncology Topics
• Ovarian Cancer
• Pancreatic Cancer
• Prostate Cancer
• Renal Cell Carcinoma
• Research Updates
• Supportive Care

Resources

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This resource has been specific designed to meet the educational needs of oncology nurses. Check regularly for the latest conference coverage, treatment updates and plenty of free CE hours. Click here.

FEATURED VIDEO SEGMENT
Expert Highlight: ESAs in Cancer

David P. Steensma, MD, describes a patient-level meta-analysis on the effect of ESAs on the survival of cancer patients and the implications for patient care. Click here.

Denosumab Produces Consistent Increases in Bone Mineral Density in Women With Breast Cancer and Men With Prostate Cancer Receiving Hormone-Ablation Therapy

Following 24 months of adjuvant aromatase inhibitor therapy in women with breast cancer and androgen deprivation therapy in men with prostate cancer, denosumab increased BMD at selected skeletal sites; safety profile of denosumab was similar to that of placebo.

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