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CME

Biomarker-Driven NSCLC Care: The Precision Medicine Model for Today and the Future

Multimedia
In this on-demand webcast from a recent AACR satellite symposium, expert faculty highlight the use of biomarkers to guide treatment choices in non-small-cell lung cancer, including new data, recent approvals, and treatment guidelines.

Physicians: Maximum of 1.75 AMA PRA Category 1 Credits

Released: May 12, 2022

Expiration: May 11, 2023

No longer available for credit.

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Faculty

Todd M. Bauer

Todd M. Bauer, MD

Senior Investigator, Greco-Hainsworth Centers for Research
Tennessee Oncology, PLLC
Nashville, Tennessee

Sandip P. Patel

Sandip P. Patel, MD

Professor, Medical Oncology, UC San Diego
Leader, Experimental Therapeutics
Deputy Director, Sanford Stem Cell Clinical Center
Co-Leader, Solid Tumor Therapeutics Program
Medical Director, Clinical Research Informatics
La Jolla, California

Joshua Sabari

Joshua Sabari, MD

Assistant Professor of Medicine
Thoracic Medical Oncology
NYU Langone Health
Perlmutter Cancer Center
NYU Grossman School of Medicine
New York, NY

Provided by

Provided by Clinical Care Options, LLC
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Supporters

Supported by educational grants from

Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC

Lilly

Novartis Pharmaceuticals Corporation

Turning Point Therapeutics Inc

Target Audience

This program is intended for physicians and other healthcare professionals who care for patients with NSCLC.

Learning Objectives

Upon completion of this activity, participants should be able to:
  • Assess new and emerging predictive biomarkers to guide treatment decisions for individual patients with all stages of NSCLC
  • Plan therapeutic strategies for patients with NSCLC based on available evidence, tumor molecular profile, comorbidities, and expert recommendations
  • Discuss the practical aspects of biomarker testing and interpretation, including benefits/limitations of different testing methodologies/platforms/assays, along with racial, age, and socioeconomic disparities
  • Identify existing disparities in care and barriers to biomarker testing and clinical trial enrollment for all patients with NSCLC

Disclosure

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Faculty Disclosure

Primary Author

Todd M. Bauer, MD

Senior Investigator, Greco-Hainsworth Centers for Research
Tennessee Oncology, PLLC
Nashville, Tennessee

Todd M. Bauer, MD, has disclosed that he has received funds for research support paid to his institution from AbbVie, Aileron, Amgen, ARMO, Astellas, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Calithera, Clovis, Daiichi Sankyo, Deciphera, Five Prime, Foundation Medicine, Genentech/Roche, GlaxoSmithKline, Ignyta, Immunocore, Immunogen, Incyte, Jacobio, Janssen, Karyopharm, Kolltan, Leap, Lilly, Loxo, MabVax, MedImmune, Medpacto, Merck, Merrimack, Millennium, Mirati, Moderna, Novartis, Onyx, Pfizer, Peleton, Phosplatin Therapeutics, Principa Biopharma, Roche, Sanofi, Stemline, Takeda, and Top Alliance BioScience; consulting fees from Blueprint Medicines, Exelixis, Ignyta, Guardant Health, Loxo, Moderna, and Pfizer; has received fees for non-CME/CE services from Astellas, AstraZeneca, Celgene, Clovis Oncology, EMD Serono, Genentech, Lilly, Merck, Novartis, Pharmacyclics, Pfizer, and Sysmex; and has served on a speakers’ bureau for Bayer.

Sandip P. Patel, MD

Professor, Medical Oncology, UC San Diego
Leader, Experimental Therapeutics
Deputy Director, Sanford Stem Cell Clinical Center
Co-Leader, Solid Tumor Therapeutics Program
Medical Director, Clinical Research Informatics
La Jolla, California

Sandip P. Patel, MD, has disclosed that he has received funds for research support from Amgen, AstraZeneca/MedImmune, Bristol-Myers Squibb, Fate Therapeutics, Iovance, Lilly, Merck, Pfizer, Roche/Genentech, and SQZ Biotechnologies and consulting fees from Amgen, AstraZeneca, Bristol-Myers Squibb, Certis, Genentech, Illumina, Lilly, Merck, Pfizer, Rakuten, and Tempus.

Joshua Sabari, MD

Assistant Professor of Medicine
Thoracic Medical Oncology
NYU Langone Health
Perlmutter Cancer Center
NYU Grossman School of Medicine
New York, NY

Joshua Sabari, MD, has disclosed that he has received consulting fees from AstraZeneca, Genentech, Janssen, Mirati, Navire, Pfizer, Regeneron, Sanofi Genzyme, and Takeda.

Staff Disclosure

Staff

Gordon Kelley,

Clinical Editor
Clinical Care Options, LLC

Gordon Kelley has no relevant conflicts of interest to report.

Krista Marcello,

Associate Managing Editor

Krista Marcello has no relevant conflicts of interest to report.

Kevin Obholz, PhD

Editorial Director, Hematology/Oncology

Kevin Obholz, PhD, has no relevant conflicts of interest to report.

Brian Purves, PharmD, MBA

Brian Purves has disclosed he was an employee of AstraZeneca (employment ended 8/2021).

Timothy A. Quill, PhD

Senior Managing Editor

Timothy A. Quill, PhD, has no relevant conflicts of interest to report.

Kristen Rosenthal, PhD

Clinical Editor

Kristen Rosenthal, PhD, has no relevant conflicts of interest to report.

Justine Stanley, MSc

Editorial Contributor

Justine Stanley has no relevant conflicts of interest to report.

Instructions for Credit

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Credit Designation

CCO designates this enduring material for a maximum of 1.75 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Additional Information

Participation in this self-study activity should be completed in approximately 1.75 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from May 12, 2022, through May 11, 2023:

1. Register online at http://www.clinicaloptions.com.
2. Read the target audience, learning objectives, and faculty disclosures.
3. Study the educational activity online or printed out.
4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65% and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the posttest confirmation page. Records of all CME/CE activities completed can be found on the "CME/CE Manager" page. There are no costs/fees for this activity.

Program Medium

This program has been made available online.


Goal


The goal of this program is to improve the knowledge and competence of learners to optimally assess biomarkers and then effectively and safely integrate novels agents into their practice for patients with NSCLC.