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CCO Treatment Updates

Focus on the Virus: A New Paradigm for the Management and Treatment of HBV

Understanding HBV: Viral Load and Disease Progression

Module 1 of 3

CME Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Ching-Lung Lai, MD
  • Ching-Lung Lai, MD

CREDIT INFORMATION

Release Date: October 31, 2006

Expiration Date: October 30, 2007


Physicians: maximum of 0.75 AMA PRA Category 1 Credits

Registered Nurses: 0.9 Nursing contact hours

Status: The activity is not currently available for credit.

Begin the Module

Ching-Lung Lai, MD, discusses data indicating the importance of HBV DNA levels in disease progression, and the potential mechanisms underlying this relationship.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe the significance of HBV DNA levels in patients infected with HBV in early childhood
  • Recount data regarding the role of viral load on disease progression in patients infected with HBV
  • Discuss the role of HBV DNA in choosing when to treat and in evaluating on-treatment outcomes as described in current treatment guidelines

New Measures of Treatment Success: Recent Data on Potency and On-Treatment Response

Module 2 of 3

CME Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Robert G. Gish, MD
  • Robert G. Gish, MD

CREDIT INFORMATION

Release Date: October 31, 2006

Expiration Date: October 30, 2007


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Registered Nurses: 1.0 Nursing contact hour

Status: The activity is not currently available for credit.

Begin the Module

Robert G. Gish, MD, discusses the latest clinical evidence regarding the importance of drug potency and long-term therapy in achieving optimal outcomes in the treatment of chronic hepatitis B.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe the role of HBV DNA levels in the management of patients with chronic hepatitis B
  • Review the clinical data for approved and investigational agents for the treatment of chronic hepatitis B
  • Discuss the relationship between viral suppression and outcomes in the management of patients with chronic hepatitis B

Management of Resistance: Implications for Treatment Choice

Module 3 of 3

CME Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Jean-Michel Pawlotsky, MD, PhD
  • Jean-Michel Pawlotsky, MD, PhD

CREDIT INFORMATION

Release Date: October 31, 2006

Expiration Date: October 30, 2007


Physicians: maximum of 0.75 AMA PRA Category 1 Credits

Registered Nurses: 0.9 Nursing contact hours

Status: The activity is not currently available for credit.

Begin the Module

Jean-Michel Pawlotsky, MD, PhD, reviews clinical strategies for preventing and managing drug resistance in patients with chronic hepatitis B.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Review current data regarding causes and rates of HBV resistance
  • Describe prevention strategies for reducing the risk of HBV resistance development
  • Discuss management strategies for hepatitis B patients with resistance to antivirals

Interactive Case Challenges

Management of an HBeAg-Negative Patient With Cirrhosis and Elevated Alanine Aminotransferase

CME Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Robert G. Gish, MD
  • Robert G. Gish, MD

CREDIT INFORMATION

Release Date: October 31, 2006

Expiration Date: October 30, 2007


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Registered Nurses: 1.4 Nursing contact hours

Status: The activity is not currently available for credit.

Begin the Case Challenge

Robert G. Gish, MD, describes the management of a recently diagnosed HBeAg-negative patient presenting with elevated ALT.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe clinical data on current treatment options for chronic hepatitis B
  • Discuss factors in determining candidacy for hepatitis B therapy in HBeAg-negative patients
  • Recount data on the optimal management of hepatitis B patients with decompensated disease

Management of an HBeAg-Positive Patient With Borderline-Normal ALT and Family History of Liver Cancer

CME Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Paul Martin, MD
  • Paul Martin, MD

CREDIT INFORMATION

Release Date: October 31, 2006

Expiration Date: October 30, 2007


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Registered Nurses: 1.3 Nursing contact hours

Status: The activity is not currently available for credit.

Begin the Case Challenge

Paul Martin, MD, discusses management decisions for a patient with borderline normal ALT, a family history of hepatocellular carcinoma, and HBeAg-positive serostatus.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss patient characteristics and tests involved in deciding when to treat HBeAg-positive patients
  • Describe screening procedures for HBV-infected patients with hepatocellular carcinoma
  • List goals of therapy for patients with HBeAg-positive chronic hepatitis B

CCO Slidesets

Viral Load and Disease Progression

Download the Slideset


Format: Microsoft PowerPoint (.ppt) | File size: 814 KB | Date posted: 10/31/2006


New Measures of Treatment Success: Recent Data on Potency and On-Treatment Response

Download the Slideset


Format: Microsoft PowerPoint (.ppt) | File size: 632 KB | Date posted: 10/31/2006


Management of Resistance: Implications for Treatment Choices

Download the Slideset


Format: Microsoft PowerPoint (.ppt) | File size: 876 KB | Date posted: 10/31/2006


Disclaimer: The materials published on the Clinical Care Options Sites reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

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Educational grants support only the CME-certified components of this program.