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CCO Treatment Updates

Virologic Tools for Monitoring Patients With Chronic Hepatitis B

Module

Virologic Monitoring in Hepatitis B: Tools for Determining Treatment Candidacy and Response

Faculty:

Kris V. Kowdley, MD, FACP, FACG, FASGE, AGAF
  • Kris V. Kowdley, MD, FACP, FACG, FASGE, AGAF

CREDIT INFORMATION

Release Date: October 31, 2007

Expiration Date: October 30, 2008


Physicians: maximum of 1.25 AMA PRA Category 1 Credits

Registered Nurses: 1.2 Nursing contact hours

Status: The activity is not currently available for credit.

Begin the Module

Kris V. Kowdley, MD, FACP, FACG, FASGE, AGAF, discusses the importance of virologic tools, with a focus on HBV DNA monitoring, for deciding when to treat and evaluating on-treatment response to oral HBV agents.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • List available virologic tools for monitoring patients with chronic hepatitis B
  • Discuss the prognostic value of virologic monitoring in assessing the natural history of untreated chronic hepatitis B
  • Summarize clinical data on the use of virologic endpoints as treatment goals, and the use of virologic monitoring tools in making treatment decisions and assessing response and nonresponse to therapy

Interactive Case Challenge

Management of a 52-Year-Old HBeAg-Positive, Treatment-Naive Female Seeking Hepatitis B Therapy

Faculty:

Robert G. Gish, MD
  • Robert G. Gish, MD

CREDIT INFORMATION

Release Date: October 24, 2007

Expiration Date: October 23, 2008


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Registered Nurses: 1.0 Nursing contact hour

Status: The activity is not currently available for credit.

Begin the Case Challenge

Robert G. Gish, MD, reviews the importance of HBV DNA in determining treatment candidacy and making on-treatment decisions in hepatitis B management in this interactive case challenge.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Summarize the factors used to determine treatment candidacy in HBeAg-positive patients, including HBV DNA
  • Describe the relationships between HBV DNA levels and liver disease outcomes in HBV-infected patients
  • List the definitions of response in hepatitis B and methods for identifying them

Interactive Tool

HBV DNA Monitoring for Oral Agents

Launch Tool


This interactive tool tracks a patient’s progress on therapy by calculating and graphically representing changes in HBV DNA over time. The tool also generates key patient evaluation dates and interprets the patient progress over time by highlighting response patterns and tailoring responses according to treatment history. The tool has the capability to save patient data only on the end-user’s computer, making it available for editing upon subsequent uses.


Format: Adobe Flash (.swf) | File size: 615 KB


Disclaimer: The materials published on the Clinical Care Options Sites reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

Contact Info

An unrestricted educational grant provided by:

Educational grants support only the CME-certified components of this program.