Learning Objectives

Upon completion of this activity, participants should be able to:

• List available virologic tools for monitoring patients with chronic hepatitis B
• Discuss the prognostic value of virologic monitoring in assessing the natural history of untreated chronic hepatitis B
• Summarize clinical data on the use of virologic endpoints as treatment goals, and the use of virologic monitoring tools in making treatment decisions and assessing response and nonresponse to therapy

Learning Objectives

Upon completion of this activity, participants should be able to:

• Summarize the factors used to determine treatment candidacy in HBeAg-positive patients, including HBV DNA
• Describe the relationships between HBV DNA levels and liver disease outcomes in HBV-infected patients
• List the definitions of response in hepatitis B and methods for identifying them

This interactive tool tracks a patient’s progress on therapy by calculating and graphically representing changes in HBV DNA over time. The tool also generates key patient evaluation dates and interprets the patient progress over time by highlighting response patterns and tailoring responses according to treatment history. The tool has the capability to save patient data only on the end-user’s computer, making it available for editing upon subsequent uses.