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CCO Treatment Updates

Case Debates With the Experts: Applying the Updated Practice Guidelines to the Management of Hepatitis B

Interactive Case Challenges

Management of a Treatment-Naive, HBeAg-Positive, Asian American Patient

Program Director: Norah Terrault, MD, MPH

Faculty:

Jules L. Dienstag, MD
  • Jules L. Dienstag, MD

CREDIT INFORMATION

Release Date: 11/03/07

Expiration Date: 11/02/08


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Status: Please log in to view status

Begin the Case Challenge

Jules L. Dienstag, MD, reviews the factors involved in selecting the optimal treatment in patients seeking first-line therapy for hepatitis B.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Recount the treatment criteria for determining when to begin therapy in an HBeAg-positive patient
  • Discuss the clinical data regarding the agents available to treat chronic hepatitis B
  • Summarize factors that determine how long one should continue therapy after seroconversion in HBeAg-positive patients

Management of an HBeAg-Positive Patient on Active Antiviral Therapy Who Has Failed to Achieve a Primary Response

Program Director: Norah Terrault, MD, MPH

Faculty:

Nezam H. Afdhal, MD, FRCPI
  • Nezam H. Afdhal, MD, FRCPI

CREDIT INFORMATION

Release Date: 11/03/07

Expiration Date: 11/02/08


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Status: Please log in to view status

Begin the Case Challenge

Nezam H. Afdhal, MD, FRCPI, reviews management strategies for an HBeAg-positive Asian patient with chronic HBV infection.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • List the definitions of nonresponse and resistance in hepatitis B and strategies for identifying these response patterns
  • Describe the AASLD guideline recommendations for management of primary nonresponse and discuss the merits of each strategy
  • Summarize how continued treatment during suboptimal response relates to antiviral resistance rates

Management of an HBeAg-Negative Patient With Lamivudine Resistance

Program Director: Norah Terrault, MD, MPH

Faculty:

Emmet B. Keeffe, MD, MACP
  • Emmet B. Keeffe, MD, MACP

CREDIT INFORMATION

Release Date: 11/03/07

Expiration Date: 11/02/08


Physicians: maximum of 1.0 AMA PRA Category 1 Credit

Status: Please log in to view status

Begin the Case Challenge

Emmet B. Keeffe, MD, MACP, describes treatment strategies for managing emergence of lamivudine resistance in a patient with HBeAg-negative chronic hepatitis B.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Recall the optimal treatment strategies for HBeAg-negative chronic hepatitis B
  • Discuss how the initial treatment strategies for HBeAg-negative chronic hepatitis B can affect future treatment options
  • Summarize management strategies for patients who have resistance toward 1 or more antiviral agents

CCO Slidesets

Debate: Nucleos(t)ide Analogues vs Peginterferon in Treatment-Naive HBeAg-Positive Patients

Download the Slideset


Robert P. Perrillo, MD, and Jules L. Dienstag, MD, debate the use of peginterferon vs nucleos(t)ide analogues as first-line therapy for HBeAg-positive hepatitis B patients.


Format: Microsoft PowerPoint (.ppt) | File size: 734 KB | Date posted: 11/4/2007


Debate: What Is the Best Rescue Strategy for the Management of Primary Nonresponse: Switch or Add?

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Robert G. Gish, MD, and Nezam H. Afdhal, MD, FRCPI, debate the optimal strategy for management of hepatitis B patients with primary nonresponse.


Format: Microsoft PowerPoint (.ppt) | File size: 690 KB | Date posted: 2/17/2010


Debate: What Is the Optimal Management Strategy for Lamivudine Resistance in HBeAg-Negative Patients?

Download the Slideset


Robert G. Gish, MD, and Robert P. Perrillo, MD, evaluate the best strategies for managing lamivudine resistance in patients with hepatitis B.


Format: Microsoft PowerPoint (.ppt) | File size: 841 KB | Date posted: 2/17/2010


Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

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