...

Expert Analysis

Advances in HBV Treatment With Approved Agents

Source: CCO Official Conference Coverage of the 2008 AASLD Meeting*

*CCO is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.

Advances in HBV Treatment With Approved Agents


Faculty:

Jules L. Dienstag, MDRobert G. Gish, MDIra M. Jacobson, MD
  • Jules L. Dienstag, MD
  • Robert G. Gish, MD
  • Ira M. Jacobson, MD

CREDIT INFORMATION

Release Date: 12/24/08

Expiration Date: 12/23/09


Physicians: maximum of 1.25 AMA PRA Category 1 Credits

Registered Nurses: 1.3 Nursing contact hours

Pharmacists: 1.3 contact hours (0.13 CEUs)

Status: Please log in to view status


Begin the Expert Analysis

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Summarize new data on the efficacy and safety of approved antiviral agents for the frontline treatment of chronic HBV infection
  • Discuss the efficacy of frontline treatments for HBV infection in preventing or managing HBV resistance
  • Describe factors associated with long-term response to antiviral therapy in patients with chronic hepatitis B
  • Compare potential switch strategies for patients failing first-line antiviral treatment for chronic HBV infection
  • Recount data on HBV reactivation in carriers treated with immunomodulatory therapy

Topics covered include:

  • ETV-901: Long-term Entecavir Treatment in Nucleos(t)ide-Naive Patients
  • Entecavir Efficacy and Resistance in a Large Clinical Population of Nucleos(t)ide-Naive Patients
  • Efficacy and Safety of Tenofovir at 96 Weeks in Treatment-Naive HBV Patients
  • Week 12 On-Treatment HBsAg Level as a Predictor of Long-term Response to Peginterferon alfa-2a Therapy in HBeAg-Negative Patients
  • Predictors of SVR and HBsAg Clearance Following Long-term Adefovir Treatment in HBeAg-Negative Patients
  • Efficacy of Peginterferon alfa-2a in HBeAg-Positive Patients With Lamivudine Resistance
  • Entecavir vs Adefovir in Patients With Lamivudine Resistance Awaiting Liver Transplantation
  • Switch to Tenofovir Following Suboptimal Response to Entecavir
  • Combination Entecavir Plus Tenofovir for Multidrug-Resistant HBV
  • HBV Reactivation Following Rituximab Treatment
  • Posttransplantation HBV Recurrence With Antiviral and/or HBIG Treatment
  • Association Between Liver Fibrosis/Cirrhosis and ALT Levels

Abstract


Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

Contact Info

Educational grants provided by:

Educational grants support only the CME-certified components of this program.