Module

Factors Associated With Long-term Success With First-line Regimens

Source: An Eye on the Future: Planning for Long-term Antiretroviral Success

Factors Associated With Long-term Success With First-line Regimens

Program Director: W. David Hardy, MD

Faculty:

Renslow Sherer, MD

CREDIT INFORMATION

Release Date: February 13, 2009

Expiration Date: February 12, 2010

Physicians: maximum of 1.5 AMA PRA Category 1 Credits™

Registered Nurses: 1.4 Nursing contact hours

Status: The activity is not currently available for credit.

Learning Objectives

Upon completion of this activity, participants should be able to:

Describe patient and viral factors that may impact long-term success of first-line antiretroviral regimens
Discuss clinical trials of antiretroviral agents that support long-term efficacy and tolerability of agents
Explain how short-term and long-term adverse events associated with use of antiretroviral agents may affect use in the long term
Relate how patient comorbidities may affect choice of antiretroviral agents, with emphasis on long-term use of agents

Topics covered include:

Epidemiologic Evidence for Success of First-line HAART
Early Initiation of Antiretroviral Therapy Is a Critical Factor Determining Long-term Success
Preferred First-line Antiretroviral Regimens
Preferred Antiretroviral Agents: NNRTIs and PIs
Preferred Antiretroviral Agents: NRTIs
Newer Agents for First-line Therapy
Regimen Convenience and Adherence
Patient Factors Determining Long-term Success of First-line HAART
Viral Factors Determining Long-term Success of First-line HAART: Baseline HIV-1 RNA and Resistance
Impact of Physician Expertise on Long-term Success of First-line HAART
Conclusion

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