CCO Treatment Updates

Managing Drug-Drug Interactions in the Changing Landscape of HIV

Drug-Drug Interactions in the Treatment of HIV

Module 1 of 1

Faculty:

Courtney V. Fletcher, PharmD headshot
  • Courtney V. Fletcher, PharmD

CME CREDIT INFORMATION

Release Date: 05/15/07

Expiration Date: 05/14/08


Physicians: maximum of 1.75 AMA PRA Category 1 Credit(s)

Status: Please log in to view status



Courtney V. Fletcher, PharmD, reviews data on common drug-drug interactions affecting FDA-approved antiretroviral agents as well as those in expanded access programs and provides recommendations on some of the more difficult interactions that physicians face in clinical practice.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss the most common mechanisms underlying drug-drug interactions between antiretroviral agents and other medications commonly used by HIV-infected patients
  • Describe common drug-drug interactions affecting US Food and Drug Administration–approved antiretroviral agents and detail dose adjustments where appropriate
  • List combinations of antiretroviral agents and other medications that are contraindicated
  • Summarize common drug-drug interactions affecting investigational antiretrovirals currently available through expanded access programs

Interactive Tool

Drug-Drug Interactions Tool: From the CME-certified program Managing Drug-Drug Interactions in the Changing Landscape of HIV


Faculty:

 
  • Charles W. Flexner, MD
  • Paul Pham, PharmD, BCPS
This interactive tool will enable readers to select a specific antiretroviral agent from a listing of all FDA-approved agents, and either:
  • Display and print a report of the interactions between this drug and other antiretroviral agents and commonly prescribed concomitant medications, or
  • Select multiple concomitant agents from a listing of those most commonly used by HIV-infected patients, and create a report on any interactions between the selected antiretroviral agents and other non-antiretroviral medications.

Format: Adobe Flash | File size: 134 KB


Drug-Drug Interactions in HIV-Infected Patients: A Downloadable Tool for Mobile Devices

This unique downloadable tool for Palm and Pocket PC/Windows Mobile handheld devices allows you to:

  • Search for interactions between antiretrovirals and other medications frequently prescribed for HIV-infected patients
  • Stay up-to-date on pharmacokinetic interactions for the most recently approved antiretroviral agents, including fixed-dose coformulations
  • Review contraindications and potential interactions, adjusted for the impact of ritonavir boosting on specific interactions
  • Receive recommendations on how to resolve contraindications or manage interactions
  • Look up interactions by drug brand names and/or generic names

Tool Version 1.2.  Data last updated November 20, 2007.

 

Download to Hand-held Devices

DOWNLOADABLE FORMATS

Pocket PC / Windows Mobile executable

Format: Pocket PC | File size: 14.72 MB


  • Device Compatibility
    • Pocket PC 2003/Windows Mobile 5
    • Touchscreen required
    • 3.7 MB available memory
  • PC Compatibility
    • Windows 2000 or later
    • Microsoft ActiveSync
  • Instructions
    • Connect device to PC and start ActiveSync
    • Download EXE to PC
    • Run EXE and follow onscreen instructions
Pocket PC / Windows Mobile zipped file

Format: Pocket PC | File size: 2.79 MB


  • Connect device to PC and start ActiveSync
  • Download zip file to PC
  • Extract files
  • Run EXE file
Palm OS executable

Format: Palm | File size: 3.79 MB


  • Device Compatibility
    • Color Palm, minimum resolution 320x320 (Zire devices not supported)
    • Palm OS 4 or later
    • 3.7 MB available memory
  • PC Compatibility
    • Windows 2000 or later
    • Palm Desktop
  • Instructions:
    • Connect device to PC and start Palm Desktop
    • Download EXE to PC
    • Run EXE
    • HotSync the device
Palm OS zipped file

Format: Palm | File size: .76 MB


  • Connect device to PC and start Palm Desktop
  • Download zip file to PC
  • Extract files
  • Run EXE file
  • HotSync the device
Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Medical Education Collaborative and Clinical Care Options, LLC.

Contact Info

Educational grant provided by:

Educational grants support only the CME-certified components of this program.