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  • Single Pill vs Multicomponent Regimens: What Is the Impact on Patients?

    Charles B. Hicks MD - 2/24/2015
    In 2015, most HIV-infected persons initiating first-line ART are prescribed a once-daily single-tablet regimen. I describe a recent complex case that made treatment selection challenging.
  • Will the Resistance Record With Newer Therapies Hold Up in Clinical Practice? Here’s My Take

    Mark A. Wainberg PhD - 2/23/2015
    How I approach first-line therapy in my practice in light of clinical trial data demonstrating a high barrier to dolutegravir resistance.
  • What Does the IPERGAY Trial Tell Us About the Future of PrEP?

    Kevin M. O'Hara PA - 2/5/2015
    Should on-demand dosing of oral PrEP become the new standard for HIV prevention among high-risk individuals?
  • Changing NRTI Options Within Single-Tablet Antiretroviral Regimens

    Daniel R. Kuritzkes MD - 12/23/2014 3 comments / Last Comment: 1/12/2015
    How might the first abacavir-containing STR fit into HIV treatment strategies?
  • What the iPrEX Study Taught Me About Adherence Counseling

    Kevin M. O'Hara PA - 10/24/2014 1 comment / Last Comment: 11/7/2014
    iPrEX OLE showed that perfect adherence was not required to attain the benefits of PrEP. How should that influence our approach to adherence counseling for our patients?
  • A Quandary Over Switching: When Patients Resist My Recommendation to Switch

    David A. Wohl MD - 10/15/2014 4 comments / Last Comment: 11/26/2014
    I usually recommend patients who are still receiving lopinavir/ritonavir-based regimens to switch. But how strongly should I urge them to switch when they are reluctant?
  • To Switch or Not to Switch: Management of First-line Boosted PI Virologic Failure

    W. David Hardy MD - 10/7/2014 2 comments / Last Comment: 11/18/2014
    After a first-line boosted PI regimen fails virologically, when is it OK to stay the course vs making a regimen switch?
  • Deintensification Strategies Using Boosted PIs: Are They Ready for Prime Time?

    Paul E. Sax MD - 10/7/2014 5 comments / Last Comment: 12/27/2014
    Recent studies have highlighted the potential efficacy of 2-drug boosted PI regimens. Are you considering integrating these strategies into your practice?
  • Choosing a Single-Tablet Regimen for HIV Patients: What Do the Latest IAS-USA Guidelines Have to Say?

    Renslow Sherer MD - 10/7/2014 4 comments / Last Comment: 1/2/2015
    How I apply recent guidelines in daily practice to offer eligible patients the benefits of single-tablet regimens.
  • Sizing Up the Newest Integrase Inhibitor–Based Single-Tablet Regimen

    William G. Powderly MD - 9/22/2014 1 comment / Last Comment: 9/25/2014
    When it comes to ART, choice is good. And the recent FDA approval of the dolutegravir/abacavir/lamivudine single-tablet regimen contributes a very significant addition to our choices.
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