Expert Analysis

Investigational Antiretrovirals

Source: CCO Official Conference Coverage of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention

Investigational Antiretrovirals

Faculty:

Pedro Cahn, MD, PhD
Joseph J. Eron, Jr., MD
Daniel R. Kuritzkes, MD

CREDIT INFORMATION

Release Date: September 14, 2007

Expiration Date: September 13, 2008

Physicians: maximum of 1.25 AMA PRA Category 1 Credits™

Registered Nurses: 1.2 Nursing contact hours

Pharmacists: 1.2 contact hours (0.12 CEUs)

Status: The activity is not currently available for credit.

Learning Objectives

Upon completion of this activity, participants should be able to:

Identify investigational antiretrovirals in early or late stages of clinical development
Summarize the results of recent clinical studies involving investigational antiretrovirals
Specify which investigational agents have been studied in treatment-naive vs treatment-experienced patients

Topics covered include:

DUET-1 and -2: Assessment of Etravirine Plus Darunavir/Ritonavir-Based Regimens in Treatment-Experienced Patients
TMC278-C204 Metabolic and Safety Substudies: Investigation of Rilpivirine in Treatment-Naive Patients
7-Day Monotherapy Trial of the Next-Generation NNRTI UK-453,061
MERIT: Maraviroc vs Efavirenz in the Treatment of Antiretroviral-Naive Patients
ACTG A5211: 48-Week Study of Vicriviroc in Treatment-Experienced Patients
Phase II Trials Evaluating the Investigational CCR5 Antagonists INCB009471 and PRO 140
Comparable Antiviral Activity and Accelerated Viral Decay of Raltegravir vs Efavirenz in Treatment-Naive Patients
Apricitabine vs Lamivudine in Treatment-Experienced Patients With the M184V Mutation

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