Expert Analysis

First-Line Therapy and Switch Strategies

Source: CCO Official Conference Coverage of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention

First-Line Therapy and Switch Strategies


Faculty:

  • David A. Cooper, MD, DSc
  • Joel E. Gallant, MD, MPH
  • Kathleen E. Squires, MD

CME CREDIT INFORMATION

Release Date: 09/27/07

Expiration Date: 09/26/08


Physicians: maximum of 1.5 AMA PRA Category 1 Credit(s)

Pharmacists: 1.5 contact hours (0.15 CEUs)

Registered Nurses: 1.5 Nursing CE credits

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Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss recent data on first-line antiretroviral therapy options
  • Describe the results of recent clinical studies concerning switch strategies
  • Describe findings concerning antiretroviral therapy initiation in treatment-naive populations

Topics covered include:

  • SMART Subgroup Analysis in Naive and Untreated Patients
  • Maraviroc vs Efavirenz in Treatment-Naive Patients
  • Raltegravir vs Efavirenz in Treatment-Naive Patients
  • Long-term Follow-up of Tenofovir-Based Regimens
  • Switching NRTIs to Tenofovir/Emtricitabine or Abacavir/Lamivudine
  • Boosted Saquinavir vs Boosted Lopinavir in Treatment-Naive Patients
  • Boosted Atazanavir vs Boosted Fosamprenavir in Treatment-Naive Patients
  • Boosted vs Unboosted Atazanavir in Treatment-Naive Patients
  • Lopinavir/Ritonavir Plus 1 or More NRTIs in Therapy-Naive Patients
  • Lopinavir/Ritonavir Monotherapy in Therapy-Naive Patients
  • Early vs Later Antiretroviral Initiation in HIV-Infected Infants
  • Conclusion


Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

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