Learning Objectives
Upon completion of this activity, participants should be able to:
- Describe the depletion of CD4+ T cells in the gastrointestinal tract following HIV-1 infection
- Discuss immune activation following HIV-1 infection and its effects on the T-cell population in the gastrointestinal tract
- Explain how early HAART may have a greater effect on repopulating the CD4+ T-cell population in the gut than treatment during chronic infection
Topics covered include:
- GI Tract Damage in HIV-1 Infection
- Consequences of Immune Activation
- Progression to AIDS
- HAART and the GI Tract
- GI Damage in Nonprogressive Infection
- Summary: Implications for Clinical Practice
Abstract