Learning Objectives
Upon completion of this activity, participants should be able to:
- Discuss the findings of studies regarding the relationships among HIV infection, antiretroviral therapy, and the development of non-AIDS events in HIV-infected patients
- Describe data that indicate differences in life expectancy between treated HIV-infected patients and those who are uninfected
- Summarize potential mechanisms for the interaction between HIV infection and development of non-AIDS events
Topics covered include:
- Introduction
- Untreated HIV Disease Increases the Risk of Diseases Associated With Aging
- Life Expectancy in Antiretroviral-Treated Patients Is Lower Than in the General Population and Predicted by CD4+ T-Cell Counts
- HIV Infection Is Associated With Increased Risk of Age-Associated Non-AIDS Diseases
- Mechanisms for Premature Aging and Increased Risk of Non-AIDS Morbidity/Mortality During Long-term HAART
- Inflammation and HIV-Associated Aging
- Mechanisms for Persistent Inflammation During HAART
- Conclusions