Module

Mechanisms of Immune Deficiency in HIV Infection

Source: HIV/AIDS Annual Update 2007

Mechanisms of Immune Deficiency in HIV Infection

Faculty:
Michael M. Lederman, MD

CME CREDIT INFORMATION

Release Date: 07/05/07

Expiration Date: 07/04/08

Physicians: maximum of 1.0 AMA PRA Category 1 Credit(s)™

Pharmacists: 1.0 contact hour (0.1 CEUs)

Registered Nurses: 1.0 Nursing CE credit

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Learning Objectives

Upon completion of this activity, participants should be able to:

Describe current knowledge about the determinants of CD4+ T-cell loss in HIV infection
Discuss the relationship between HIV replication and CD4+ T-cell losses in HIV infection
Summarize the relationship between immune activation and immune deficiency in HIV infection

Topics covered include:

Introduction
Predictive Value of Plasma HIV Levels
Importance of Immune Activation in HIV Infection
Lymphocyte Turnover in Chronic HIV Infection
Potential Drivers of Immune Activation in HIV Infection
Central Memory T Cells in HIV Pathogenesis
Role of Cytokines in the T-Cell Turnover of HIV Infection
Summary: Implications for Clinical Practice

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