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Andrew Carr, MBBS, MD, FRACP, FRCP; Anton L. Pozniak, MD, FRCP; and Kimberly Y. Smith, MD, MPH, discuss key studies pertaining to the management of HIV infection in developed nations presented at the 2009 International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention with a focus on the implications of those findings for clinical practice.
Learning Objectives
Upon completion of this activity, participants should be able to:
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Summarize the latest clinical findings on potential associations between use of antiretroviral agents and cardiovascular disease risk
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Describe recent data on the relative efficacy of antiretroviral therapy in treatment-experienced women vs men
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Discuss new results from clinical trials investigating drug class-sparing regimens and other treatment simplification strategies
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Cite the most recent data on the safety and efficacy of new antiretroviral agents
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Articulate new findings from studies evaluating prevalence and risk factors for bone mineral density loss and vitamin D deficiency among HIV-infected patients
Topics covered include:
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Abacavir Exposure, Chronic Kidney Disease, and Risk of Cardiovascular Disease Risk in a VA Cohort
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BICOMBO Substudy: Abacavir and Tenofovir Exposure and Biomarkers of Cardiovascular Dysfunction
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Case-Control Study of Quebec’s Public Health Insurance Database: NRTI or PI Exposure and Risk of Acute MI
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GRACE: Safety and Efficacy of Darunavir/Ritonavir in Treatment-Experienced Women vs Men
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FOTO: 5-Days-On, 2-Days-Off vs Standard Efavirenz, Tenofovir, Emtricitabine Dosing
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Switch to Raltegravir Plus Unboosted Atazanavir in Treatment-Experienced Patients
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ARIES: Simplifying First-line Atazanavir/Ritonavir to Atazanavir Following Virologic Suppression
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Switch From Stable HAART to Darunavir/Ritonavir Monotherapy
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Once-Daily vs Twice-Daily Lopinavir/Ritonavir Plus 2 NRTIs in Treatment-Experienced Patients
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MERIT-ES: Maraviroc vs Efavirenz at Week 96 in Treatment-Naive Patients
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ARTEN: First-line Atazanavir/Ritonavir vs Nevirapine
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Dose-Ranging Study of Novel Integrase Inhibitor, S/GSK1349572, in HIV-Infected Patients
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SPAR Substudy: Bone Mineral Density Loss With NRTI- vs PI-Sparing Regimens
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Risk Factors for Vitamin D Deficiency Among HIV-Infected Patients in a United Kingdom Cohort
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ESPRIT, SILCAAT, and STALWART: Clinical Utility of IL-2 Therapy in HIV-Infected Patients
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Faculty
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Andrew Carr
MBBS, MD, FRACP
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Anton L. Pozniak
MD, FRCP
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Kimberly Y. Smith
MD, MPH
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Credit Information
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